Cadillac Escalade Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Cadillac Escalade with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Cadillac Escalade—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Cadillac Escalade weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Cadillac Escalade, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Cadillac Escalade.

1999-2000 Cadillac Escalade Rear Hatch Weatherstrip Seal, '92-'00 GM Full Size SUV 2 and 4 Door Models.

Designed for GM full-size SUVs from 1992 to 2000, this rear hatch seal is a perfect fit for 2-door and 4-door models, replacing OEM part #15758707. Crafted with precision, it features an accurate seal profile and is made from durable dual-hardness EPDM polymer, ensuring long-lasting performance. This seal effectively reduces drafts and road noise, enhancing your driving comfort. It fits a wide range of vehicles, including Chevrolet Blazer, Suburban, Tahoe, GMC Yukon, and Cadillac Escalade models from 1992 to 2000. Easy to install, this seal is designed to snugly fit the rear hatch, providing a weatherproof barrier to keep out moisture and debris. Backed by a 90-day hassle-free warranty, this part guarantees quality and reliability for your vehicle.

Features and Benefits
  • Reduces drafts and road noise for a quieter ride.
  • Made with durable dual-hardness EPDM polymer for longevity.
  • Provides a weatherproof seal to protect against moisture and debris.
  • Easy to install for a snug, secure fit.

$117.99
• SALE $94.95
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1999-2000 Cadillac Escalade Rear Hatch Weatherstrip Seal, '92-'00 GM Full Size SUV 2 and 4 Door Models.
2000-2006 Cadillac Escalade Rear Door Weatherstrip Seal.

Designed for rear doors, this seal fits the 2000-2006 Chevrolet Tahoe, Cadillac Escalade, and GMC Denali/Yukon trucks, specifically for the rear left and right sides of the body. This high-quality rear door seal is crafted by SUPERsoft, known for producing parts that are 30% softer and more durable than other brands. It ensures a snug, weatherproof fit to keep out water, wind, and noise, enhancing the comfort and longevity of your vehicle. Unlike other seals, this one is made without accelerants or cheap fillers, preventing premature aging or cracking over time. Installation is straightforward, as the seal is designed to fit perfectly into the original door frame grooves, restoring the factory look and function. Backed by a 90-day warranty, this seal is a reliable choice for maintaining your vehicle's performance and appearance.

Features and Benefits
  • Keeps water, wind, and noise out for a quieter ride.
  • Made from durable, long-lasting materials without cheap fillers.
  • Easy to install with a precise fit for rear doors.
  • Enhances the vehicle's comfort and protects against the elements.

$118.49
• SALE $94.95
Select Color/Material Options  
2000-2006 Cadillac Escalade Rear Door Weatherstrip Seal.
2007-2014 Cadillac Escalade Door Weatherstrip Seal, 07-13 GM Standard, Crew Cab Trucks and 4 Door Sport Utility Vehicles.

Designed for trucks and SUVs, this door seal fits 2007-2014 Chevrolet Avalanche, Silverado, Suburban, and Tahoe models, as well as GMC Sierra, Yukon, and Yukon XL vehicles, including Cadillac Escalade series from the same years. Made of durable EPDM polymer, this seal ensures a snug fit for front or rear door openings, left or right side, and mounts directly on the body. Its accurate seal profile effectively reduces drafts and road noise, enhancing cabin comfort. With an OEM fit at a fraction of the cost, it’s a reliable replacement that restores your vehicle’s weatherproofing and soundproofing. Backed by a 90-day hassle-free warranty, this part is a practical and affordable solution for maintaining your vehicle’s performance and comfort.

Features and Benefits
  • Provides a tight seal to block drafts and noise.
  • Made from durable EPDM polymer for long-lasting use.
  • Fits front or rear doors, left or right side, on body.
  • Easy installation with OEM fit for a seamless replacement.

$141.49
• SALE $112.95
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2007-2014 Cadillac Escalade Door Weatherstrip Seal, 07-13 GM Standard, Crew Cab Trucks and 4 Door Sport Utility Vehicles.
2000-2006 Cadillac Escalade Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV 4 Door, On Body, Pair.

Designed for the 2000-2006 Cadillac Escalade, Chevrolet Suburban 1500/2500, Chevrolet Tahoe, GMC Yukon, and GMC Yukon XL 1500/2500 trucks, these high-quality door seals are crafted to mount on the upper part of the body, ensuring a snug fit against the doors. Made from durable, ozone-resistant EPDM rubber, these seals are built to last and maintain their flexibility over time. Their precise design incorporates all original details, providing an accurate seal profile that reduces drafts and road noise, enhancing your driving comfort. This pair includes seals for both the left and right sides, offering a complete solution for your vehicle. Backed by a 90-day warranty, these seals are a reliable choice for restoring or maintaining your truck’s weatherproofing and sound insulation.

Features and Benefits
  • Made from ozone-resistant EPDM rubber for long-lasting durability.
  • Reduces drafts and road noise for a quieter ride.
  • Precisely designed for a perfect fit and seal.
  • Includes seals for both left and right sides for complete coverage.

$153.99
• SALE $122.95
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2000-2006 Cadillac Escalade Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV 4 Door, On Body, Pair.
2007-2017 Cadillac Escalade TG 10-T - Liftgate Weatherstrip Seal, Push-On Trim Style, On Body, Each.

Designed for 4-door trucks, this liftgate seal fits 2007-2014 Cadillac Escalade (ESV, EXT), Chevrolet Tahoe/Suburban (1500, 2500), and GMC Yukon (XL 1500, XL 2500) models, replacing OEM #22775503. Crafted from durable EPDM polymer, this seal ensures a snug fit to keep your climate-controlled air inside while blocking out weather, drafts, and road noise. Its robust construction resists wear and tear, providing long-lasting performance. The seal is easy to install, fitting securely around the liftgate to maintain a tight barrier against the elements. With its sleek black finish, it blends seamlessly with your vehicle's design, enhancing both function and appearance. Backed by a 90-day warranty, this part offers peace of mind and reliable protection for your vehicle.

Features and Benefits
  • Keeps out weather and drafts for a comfortable interior.
  • Reduces road noise for a quieter ride.
  • Made from durable EPDM polymer for long-lasting use.
  • Easy to install and fits securely for reliable performance.

$157.99
• SALE $126.95
Select Color/Material Options  
2007-2017 Cadillac Escalade TG 10-T - Liftgate Weatherstrip Seal, Push-On Trim Style, On Body, Each.

(45 Total Products)