Cadillac Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Cadillac with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Cadillac —restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Cadillac weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Cadillac , or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Cadillac .

2007-2013 Cadillac Escalade EXT Driver & Passenger Side Door Seal on body

OEM-replacement door seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22766409

2007-2014 Cadillac Escalade Driver & Passenger Side Door Seal on body

OEM-replacement door seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22766409

2007-2014 Cadillac Escalade ESV Driver & Passenger Side Door Seal on body

OEM-replacement door seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22766409

1999-1999 Cadillac Escalade Rear Liftgate Weatherstrip Seal on body

OEM-replacement rear liftgate weatherstrip seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15758707

$60.26
• SALE $41.95
Select Color/Material Options  
1999-1999 Cadillac Escalade Rear Liftgate Weatherstrip Seal on body
1979-1985 Cadillac Eldorado Sunroof Inner Pan Seal - Sunroof

OEM-replacement sunroof inner pan seal - sunroof for Buick / Cadillac / Chevrolet. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

$60.01
• SALE $41.95
Select Color/Material Options  
1979-1985 Cadillac Eldorado Sunroof Inner Pan Seal - Sunroof

(817 Total Products)