DeSoto Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your DeSoto with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your DeSoto —restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our DeSoto weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your DeSoto , or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your DeSoto .

1957-1959 DeSoto Firedome Rear Roll-Up Window Weatherstrip Seals.

Designed for 1957-1959 Chrysler, DeSoto, Dodge, and Plymouth cars and trucks, these rear roll-up window seals are 18-1/2" long and crafted specifically for the leading edge of the rear quarter window. Made with molded ends for a precise fit, they come as a pair for both the right and left sides. Manufactured by Metro Moulded Parts, these seals are built from advanced rubber compounds that resist sunlight, ozone, and chemicals, ensuring long-lasting durability. Unlike cheaper alternatives, they are free from accelerants or fillers that can cause premature aging or failure. These seals not only restore a snug, weatherproof seal to your windows but also enhance the overall appearance of your classic car. Backed by Metro’s 30-year Platinum Warranty, you can trust in their quality and longevity.

Features and Benefits
  • Provides a tight seal to prevent water and air leaks.
  • Made with durable, chemical-resistant rubber for long-term use.
  • Molded ends ensure a perfect fit for easy installation.

$91.99
• SALE $73.95
Select Color/Material Options  
1957-1959 DeSoto Firedome Rear Roll-Up Window Weatherstrip Seals.
1957-1959 DeSoto Fireflite Rear Roll-Up Window Weatherstrip Seals.

Designed for 1957-1959 Chrysler, DeSoto, Dodge, and Plymouth cars and trucks, these rear roll-up window seals are 18-1/2" long and crafted specifically for the leading edge of the rear quarter window. Made with molded ends for a precise fit, they come as a pair for both the right and left sides. Manufactured by Metro Moulded Parts, these seals are built from advanced rubber compounds that resist sunlight, ozone, and chemicals, ensuring long-lasting durability. Unlike cheaper alternatives, they are free from accelerants or fillers that can cause premature aging or failure. These seals not only restore a snug, weatherproof seal to your windows but also enhance the overall appearance of your classic car. Backed by Metro’s 30-year Platinum Warranty, you can trust in their quality and longevity.

Features and Benefits
  • Provides a tight seal to prevent water and air leaks.
  • Made with durable, chemical-resistant rubber for long-term use.
  • Molded ends ensure a perfect fit for easy installation.

$91.99
• SALE $73.95
Select Color/Material Options  
1957-1959 DeSoto Fireflite Rear Roll-Up Window Weatherstrip Seals.
1958-1959 DeSoto Firesweep Rear Roll-Up Window Weatherstrip Seals.

Designed for 1957-1959 Chrysler, DeSoto, Dodge, and Plymouth cars and trucks, these rear roll-up window seals are 18-1/2" long and crafted specifically for the leading edge of the rear quarter window. Made with molded ends for a precise fit, they come as a pair for both the right and left sides. Manufactured by Metro Moulded Parts, these seals are built from advanced rubber compounds that resist sunlight, ozone, and chemicals, ensuring long-lasting durability. Unlike cheaper alternatives, they are free from accelerants or fillers that can cause premature aging or failure. These seals not only restore a snug, weatherproof seal to your windows but also enhance the overall appearance of your classic car. Backed by Metro’s 30-year Platinum Warranty, you can trust in their quality and longevity.

Features and Benefits
  • Provides a tight seal to prevent water and air leaks.
  • Made with durable, chemical-resistant rubber for long-term use.
  • Molded ends ensure a perfect fit for easy installation.

$91.99
• SALE $73.95
Select Color/Material Options  
1958-1959 DeSoto Firesweep Rear Roll-Up Window Weatherstrip Seals.
1956 DeSoto Adventurer Rear Roll-Up Side Quarter Window Weatherstrip Seals (Fits Some Models).

Designed for 1955-1956 Chrysler, DeSoto, Dodge, and Plymouth cars and trucks, these rear roll-up side quarter window seals are crafted to fit perfectly and restore the functionality of your vehicle's windows. Made from advanced rubber compounds, these seals resist sunlight, ozone, and chemicals, ensuring long-lasting durability. Unlike cheaper alternatives, Metro Moulded Parts avoids using accelerants or fillers, which can lead to premature wear and failure. These seals are precision-molded to provide a snug fit, preventing water, air, and debris from entering your vehicle while maintaining a clean and polished look. Backed by Metro's 30-year Platinum Warranty, you can trust these seals to perform for decades.

Features and Benefits
  • Protects against water, air, and debris infiltration.
  • Made from high-quality, chemical-resistant rubber compounds.
  • Designed for a precise fit on 1955-1956 Chrysler, DeSoto, Dodge, and Plymouth models.

$97.99
• SALE $78.95
Select Color/Material Options  
1956 DeSoto Adventurer Rear Roll-Up Side Quarter Window Weatherstrip Seals (Fits Some Models).
1955-1956 DeSoto Firedome Rear Roll-Up Side Quarter Window Weatherstrip Seals (Fits Some Models).

Designed for 1955-1956 Chrysler, DeSoto, Dodge, and Plymouth cars and trucks, these rear roll-up side quarter window seals are crafted to fit perfectly and restore the functionality of your vehicle's windows. Made from advanced rubber compounds, these seals resist sunlight, ozone, and chemicals, ensuring long-lasting durability. Unlike cheaper alternatives, Metro Moulded Parts avoids using accelerants or fillers, which can lead to premature wear and failure. These seals are precision-molded to provide a snug fit, preventing water, air, and debris from entering your vehicle while maintaining a clean and polished look. Backed by Metro's 30-year Platinum Warranty, you can trust these seals to perform for decades.

Features and Benefits
  • Protects against water, air, and debris infiltration.
  • Made from high-quality, chemical-resistant rubber compounds.
  • Designed for a precise fit on 1955-1956 Chrysler, DeSoto, Dodge, and Plymouth models.

$97.99
• SALE $78.95
Select Color/Material Options  
1955-1956 DeSoto Firedome Rear Roll-Up Side Quarter Window Weatherstrip Seals (Fits Some Models).

(26 Total Products)