Ford F-450 Super Duty Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Ford F-450 Super Duty with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Ford F-450 Super Duty—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Ford F-450 Super Duty weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Ford F-450 Super Duty, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Ford F-450 Super Duty.

1999-2003 Ford F-450 Super Duty Front Door Weatherstrip Seal.

Designed for regular and quad cab trucks, this front door seal fits on the body for both the left and right sides, ensuring a snug and reliable fit for 1999-2011 Ford F-250, F-350, F-450, and F-550 Super Duty Trucks, as well as 2000-2005 Ford Excursion models. Crafted by SUPERsoft, this seal is 30% softer and more durable than other brands, providing a superior barrier against wind, water, and noise. Unlike other seals, it is made without accelerants or cheap fillers, which means it resists premature aging and cracking, ensuring long-lasting performance. The flexible material allows for easy installation, conforming perfectly to the contours of your truck’s body for a factory-like fit. Backed by a 90-day hassle-free warranty, this seal is a dependable choice for restoring comfort and protection to your vehicle.

Features and Benefits
  • Provides a tight seal to block wind, water, and noise.
  • Made with durable, high-quality materials for long-lasting use.
  • Easy to install with a precise fit for your truck’s body.
  • Designed to resist aging and cracking for reliable performance.

$133.99
• SALE $106.95
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1999-2003 Ford F-450 Super Duty Front Door Weatherstrip Seal.

(11 Total Products)