GMC Yukon XL 2500 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals
Stop leaks, drafts, and road noise in your GMC Yukon XL 2500 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your GMC Yukon XL 2500—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.
Our GMC Yukon XL 2500 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.
Use the Vehicle Selector above to find the correct weatherstrip for your GMC Yukon XL 2500, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your GMC Yukon XL 2500.
OEM-replacement liftgate upper seal on body - liftgate for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.
Replaces GM: 22845014
OEM-replacement door seal for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.
Replaces GM: 15752299
- Fitment: Driver and Passenger Side
- OEM-replacement door seal for the 2000-2006 GMC Yukon XL 2500 (GMT800)
- EPDM rubber -- resists UV, heat, ozone, and moisture
- Restores factory seal to eliminate wind noise, water leaks, and dust
- Direct fit -- installs in the factory channel without modification
For 4-door crew cab trucks, this seal, replacing OEM #21993936, is designed to press onto the upper part of the body, ensuring a snug and reliable fit. Crafted from high-quality ozone-resistant EPDM rubber, it offers durability and long-lasting performance, even in harsh weather conditions. The accurate seal profile ensures a perfect fit, making it an essential replacement for maintaining your vehicle's integrity. This hard-to-find part is compatible with 2000-2006 Chevrolet Silverado 1500, Suburban 2500, Tahoe, GMC Yukon, Yukon XL 2500, and Cadillac Escalade trucks. Its durable EPDM polymer construction resists wear and tear, providing excellent sealing to keep out water, dust, and noise. Backed by a 90-day warranty, this seal is a reliable choice for restoring your truck's functionality and comfort.
Features and Benefits- Made from ozone-resistant EPDM rubber for durability.
- Ensures a tight seal to protect against water, dust, and noise.
- Designed for a precise fit on 4-door crew cab trucks.
- Hard-to-find replacement part for 2000-2006 models.
This front door seal, measuring 163.25" long, is designed for Regular/Quad Cab and Extended Cab body styles of '99-'07 Chevrolet Silverado and GMC Sierra C/K 1500/2500 classic trucks, as well as '00-'06 Chevrolet Tahoe, Cadillac Escalade, GMC Denali/Yukon, and '02-'06 Chevrolet Avalanche and Cadillac Escalade extended cabs. It fits the front left-side and right-side on the body for most applications, with specific fitment for the front left-side only on Extended Cabs. Crafted by SUPERsoft, this seal is 30% softer and more durable than other brands, ensuring a snug, weatherproof fit that keeps out moisture, wind, and noise. Unlike other seals, it is made without accelerants or cheap fillers, preventing premature aging and cracking. This part is backed by a 90-day warranty for added peace of mind.
Features and Benefits- Provides a tight seal to block out wind, water, and noise.
- Made with durable, long-lasting materials for extended use.
- Easy to install on the front doors for a precise fit.
- Designed to maintain flexibility and performance over time.
(15 Total Products)