Cadillac Escalade Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Cadillac Escalade with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Cadillac Escalade—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Cadillac Escalade weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Cadillac Escalade, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Cadillac Escalade.

1992-2000 Cadillac Escalade Driver Side Front Door Window Run Channel Front Driver Side Glass Run Channel

  • Fitment: Driver Side
  • OEM-replacement window channel for the 1992-2000 Cadillac Escalade

$124.18
• SALE $85.95
Select Color/Material Options  
1992-2000 Cadillac Escalade Driver Side Front Door Window Run Channel Front Driver Side Glass Run Channel
1999-2000 Cadillac Escalade Driver Side Complete Glass Run Window Channel

OEM-replacement complete glass run window channel for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15001925

$124.18
• SALE $85.95
Select Color/Material Options  
1999-2000 Cadillac Escalade Driver Side Complete Glass Run Window Channel
2000-2006 Cadillac Escalade Liftgate Seal on Body

OEM-replacement liftgate seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15174843

$119.75
• SALE $82.95
Select Color/Material Options  
2000-2006 Cadillac Escalade Liftgate Seal on Body
1992-2000 Cadillac Escalade Passenger Side Front Door Window Run Channel Front Passenger Side Glass Run Channel

  • Fitment: Passenger Side
  • OEM-replacement window channel for the 1992-2000 Cadillac Escalade

$119.06
• SALE $82.95
Select Color/Material Options  
1992-2000 Cadillac Escalade Passenger Side Front Door Window Run Channel Front Passenger Side Glass Run Channel
1999-2000 Cadillac Escalade Passenger Side Complete Glass Run Window Channel

OEM-replacement complete glass run window channel for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15001926

$119.06
• SALE $82.95
Select Color/Material Options  
1999-2000 Cadillac Escalade Passenger Side Complete Glass Run Window Channel

(45 Total Products)