Cadillac Escalade Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Cadillac Escalade with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Cadillac Escalade—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Cadillac Escalade weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Cadillac Escalade, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Cadillac Escalade.

1999-2000 Cadillac Escalade Driver & Passenger Side Belt Weatherstrip Kit - Outer Driver side and Passenger side

OEM-replacement belt weatherstrip kit - outer driver side and passenger side for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15991405, 15991406

$72.72
• SALE $50.95
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1999-2000 Cadillac Escalade Driver & Passenger Side Belt Weatherstrip Kit - Outer Driver side and Passenger side
2007-2014 Cadillac Escalade Driver & Passenger Side Door Seal on body

OEM-replacement door seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22766409

1999-1999 Cadillac Escalade Rear Liftgate Weatherstrip Seal on body

OEM-replacement rear liftgate weatherstrip seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15758707

$60.26
• SALE $41.95
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1999-1999 Cadillac Escalade Rear Liftgate Weatherstrip Seal on body
2000-2004 Cadillac Escalade Driver & Passenger Side Door Lower Auxilary Weatherstrip

OEM-replacement door lower auxilary weatherstrip for Cadillac / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15758049

$54.93
• SALE $38.95
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2000-2004 Cadillac Escalade Driver & Passenger Side Door Lower Auxilary Weatherstrip
2007-2014 Cadillac Escalade Liftgate Upper Seal on body - Liftgate

OEM-replacement liftgate upper seal on body - liftgate for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22845014

$54.19
• SALE $37.95
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2007-2014 Cadillac Escalade Liftgate Upper Seal on body - Liftgate

(45 Total Products)