Ford F-250 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Ford F-250 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Ford F-250—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Ford F-250 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Ford F-250, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Ford F-250.

1969 Ford F-250 Window Crank Handle Knob and Attaching Parts. Black. Each.

This window crank handle knob and attaching parts are designed for 1969 Ford vehicles, including the Bronco Truck, Mustang Car, Thunderbird Car, and many others across Ford's lineup of trucks, cars, and vans. Crafted with precision using over 50 tons of pressure, this black knob ensures perfect definition and exact detailing, making it a reliable and visually appealing replacement. The knob is made to fit seamlessly into your vehicle's interior, restoring functionality and maintaining the classic look of your Ford. Installation is straightforward, with the included screw and clip ensuring a secure fit. Backed by Metro Moulded Parts' reputation for quality, this part is covered by a 90-day warranty for peace of mind.

Features and Benefits
  • Restores smooth window crank operation.
  • Durable black finish complements the interior.
  • Easy installation with included hardware.
  • Precision-made for a perfect fit.

$24.49
• SALE $19.95
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1969 Ford F-250 Window Crank Handle Knob and Attaching Parts. Black. Each.
1961-1966 Ford F-250 Ford Truck Instrument Cluster Housing Dash Weatherstrip Seal.

For 1961-1966 Ford F-Series trucks, this 56-inch instrument cluster seal is designed to fit perfectly and enhance your truck's interior. Made from high-quality soft-touch rubber, it ensures a snug, secure fit with its simple push-on design that installs in seconds. Crafted in the USA, this seal features rich black coloring that adds a sleek, show-car look to your dashboard while resisting fading and cracking over time. Its durable construction outperforms competing brands, providing long-lasting protection for your instrument cluster. Specifically designed for 1961-1966 Ford F-100, F-250, and F-350 trucks, this seal is a reliable upgrade for your classic vehicle. Backed by Metro's 30-year Platinum Warranty, you can trust this part to deliver exceptional performance and style for decades.

Features and Benefits
  • Easy push-on installation saves time and effort.
  • High-quality rubber resists fading and cracking.
  • Enhances your truck's interior with a rich black finish.
  • Made in the USA for trusted quality and durability.

$25.49
• SALE $20.95
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1961-1966 Ford F-250 Ford Truck Instrument Cluster Housing Dash Weatherstrip Seal.
1953-1956 Ford F-250 Radiator to Hood Weatherstrip Seal. 2-5/8" Wide X 33" Long. Each.

For 1953-1956 Ford F-100, F-250, and F-350 trucks, this radiator-to-hood seal measures 2-5/8" wide by 33" long, ensuring a precise fit for your classic vehicle. Crafted in jet black for a refined concours-quality appearance, this seal is designed to prevent air and debris from entering the engine bay, enhancing both performance and protection. Its durable construction ensures a snug and reliable fit, maintaining the integrity of your truck's engine compartment. This Metro Moulded Parts seal is backed by a 30-year warranty, giving you peace of mind and long-term confidence in your purchase.

Features and Benefits
  • Protects the engine bay from debris and airflow.
  • Jet black finish enhances the truck's classic look.
  • Precision fit for 1953-1956 Ford F-100, F-250, and F-350 trucks.

$27.49
• SALE $21.95
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1953-1956 Ford F-250 Radiator to Hood Weatherstrip Seal. 2-5/8" Wide X 33" Long. Each.
1953-1955 Ford F-250 Universal Special Purpose Grommet. 1" I.D., 2-1/2" O.D.

Designed for 1953-1955 Ford F-100, F-250, and F-350 trucks, this universal special-purpose grommet measures 1" I.D., 2-1/2" O.D., and 3/4" high, making it a perfect fit for various applications. Crafted from state-of-the-art rubber compounds, these grommets are built to resist chemicals, sunlight, and ozone, ensuring long-lasting durability and performance. Their sleek black finish and precise design provide a clean, professional look while effectively sealing and protecting openings from wear, moisture, and debris. Backed by Metro's Platinum Warranty, this pair of grommets offers 30 years of coverage, giving you peace of mind and confidence in your purchase.

Features and Benefits
  • Protects openings from wear, moisture, and debris.
  • Resistant to chemicals, sunlight, and ozone for durability.
  • Made with advanced rubber compounds for long-lasting use.

$34.99
• SALE $27.95
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1953-1955 Ford F-250 Universal Special Purpose Grommet. 1" I.D., 2-1/2" O.D.
1964-1968 Ford F-250 Clutch and Brake Pedal Pads. 3-1/4" Wide X 2-1/4" Long.

For 1964-1976 Ford trucks, vans, and cars, these clutch and brake pedal pads measure 3-1/4" wide by 2-1/4" long and are designed to fit perfectly on your vehicle's pedals. Crafted with precision, they feature detailed grooves and curves that replicate the original look, ensuring a seamless match to your classic Ford's interior. These pads are easy to install, slipping securely over the pedals to provide a firm grip and a refreshed appearance. Fitment includes a wide range of models, such as the 1964-1969 Ford Econoline Van, 1964-1968 Ford F-Series Trucks, 1965-1967 Ford Fairlane and Falcon cars, and 1973-1976 Ford Bronco. Made by Metro Moulded Parts, these pedal pads are backed by a 30-year warranty, giving you peace of mind with long-lasting quality.

Features and Benefits
  • Designed to match the original pedal look for a factory-fresh appearance.
  • Easy slip-on installation saves time and effort.
  • Durable material ensures a secure grip and long-lasting use.

$41.49
• SALE $33.95
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1964-1968 Ford F-250 Clutch and Brake Pedal Pads. 3-1/4" Wide X 2-1/4" Long.

(131 Total Products)