Ford F-250 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Ford F-250 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Ford F-250—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Ford F-250 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Ford F-250, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Ford F-250.

1953-1956 Ford F-250 Tailgate Bumper. Each.

For 1953-1956 Ford F-100, F-250, and F-350 trucks, this tailgate bumper from Metro Moulded Parts is a durable and reliable solution to protect your tailgate and truck bed from damage. Designed for easy installation, this bumper is crafted from high-quality materials to ensure long-lasting performance and strength. Its compact, rounded design fits seamlessly into place, providing a snug and secure fit that absorbs impact and reduces noise when the tailgate is closed. This part is specifically engineered to match the needs of classic Ford trucks, ensuring a perfect fit and restoring functionality to your vehicle. Backed by Metro’s Platinum Warranty, this bumper is protected for 30 years, giving you peace of mind and confidence in your purchase.

Features and Benefits
  • Protects your tailgate and truck bed from damage.
  • Reduces noise and absorbs impact when closing the tailgate.
  • Easy to install for a hassle-free upgrade.

$12.99
• SALE $10.95
Select Color/Material Options  
1953-1956 Ford F-250 Tailgate Bumper. Each.
1953-1955 Ford F-250 Sold By The Foot - Cab to Running Board Weatherstrip Seal.

This item is sold by the foot. Designed for 1953-1955 Ford F-100, F-250, and F-350 trucks, this cab-to-running board seal measures 9/16" tall and 3-5/16" wide, ensuring a precise fit for your classic truck. Made from high-quality EPDM rubber, this seal offers excellent rebound memory and long-lasting durability. Unlike foam alternatives, it resists UV light, preventing breakdown and maintaining its integrity over time. Backed by Metro Moulded Parts' 30-year Platinum Warranty, this seal is a reliable choice for restoring and protecting your vintage truck.

Features and Benefits
  • High-quality EPDM rubber resists UV damage.
  • Excellent rebound memory ensures a tight seal.
  • Customizable length sold by the foot for precise fit.

1953-1956 Ford F-250 Sold By The Foot - Top of Radiator Hood Weatherstrip Seal. 2-3/4" Wide.

This item is sold by the foot. Designed for 1953-1956 Ford F-100, F-250, and F-350 trucks, this top-of-the-radiator hood seal measures 2-3/4" wide and Crafted from high-quality EPDM extrusion, this seal offers excellent rebound memory, maintaining its shape and effectiveness over time. Unlike foam materials, it resists UV light, ensuring it won’t break down or deteriorate when exposed to the sun. This durable seal is designed to sit at the top of the radiator, creating a tight barrier to keep out dirt, water, and debris, while also helping to maintain proper airflow under the hood. Backed by Metro’s Platinum Warranty, this part is protected for 30 years, giving you peace of mind for the long haul.

Features and Benefits
  • High-quality EPDM material resists UV damage.
  • Excellent rebound memory ensures a long-lasting seal.
  • Protects the engine bay from dirt and debris.

$14.49
• SALE $11.95
Select Color/Material Options  
1953-1956 Ford F-250 Sold By The Foot - Top of Radiator Hood Weatherstrip Seal. 2-3/4" Wide.
1953-1956 Ford F-250 Battery Splash Shield. 10" X 1-5/8". Each.

This battery splash shield, measuring 10" x 1-5/8", is designed for 1953-1956 Ford F-100, F-250, and F-350 trucks. Crafted by Metro Moulded Parts, it is built with over 50 tons of pressure to ensure precise detailing and a perfect fit. This shield is essential for protecting your battery from dirt, debris, and moisture, helping to extend its life and maintain optimal performance. Its durable construction ensures it can withstand harsh conditions, making it a reliable addition to your classic truck. Backed by Metro's Platinum Warranty, this part is covered for 30 years, giving you peace of mind with your purchase.

Features and Benefits
  • Protects your battery from dirt, debris, and moisture.
  • Precision-made for a perfect fit on 1953-1956 Ford F-Series trucks.
  • Built with high pressure for exact detailing and durability.

$15.99
• SALE $12.95
Select Color/Material Options  
1953-1956 Ford F-250 Battery Splash Shield. 10" X 1-5/8". Each.
1953-1956 Ford F-250 Clutch and Brake Pedal to Floor Board Weatherstrip Seals. Pair.

Designed for 1953-1956 Ford F-100, F-250, and F-350 trucks, as well as 1954-1956 Ford Courier Sedan Delivery trucks, these clutch and brake pedal to floorboard seals are a perfect fit for your classic vehicle. Crafted with over 50 tons of pressure, these seals boast precise detailing and a flawless finish, ensuring they fit snugly and perform exceptionally. Their durable construction helps keep dirt, moisture, and debris from entering through the pedal openings, protecting your vehicle's interior and maintaining its pristine condition. These seals are easy to install, fitting directly onto the floorboard where the clutch and brake pedals pass through, providing a clean and secure seal. Backed by Metro's Platinum Warranty, you can trust these seals to last for 30 years, giving you peace of mind and confidence in your purchase.

Features and Benefits
  • Protects your vehicle's interior from dirt and moisture.
  • Precision-molded for a perfect fit and clean finish.
  • Easy installation for hassle-free replacement.

$15.99
• SALE $12.95
Select Color/Material Options  
1953-1956 Ford F-250 Clutch and Brake Pedal to Floor Board Weatherstrip Seals. Pair.

(131 Total Products)