Ford F-250 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Ford F-250 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Ford F-250—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Ford F-250 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Ford F-250, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Ford F-250.

1980-1997 Ford F-250 Driver & Passenger Side Door Seal - Upper on Door Driver Side or Passenger Side

OEM-replacement door seal - upper on door driver side or passenger side for the Ford. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces Ford: E8TZ1020518A, E9TZ1520518A, E9TZ1520519A, F0TZ1520708A

$17.99
• SALE $12.95
Select Color/Material Options  
1980-1997 Ford F-250 Driver & Passenger Side Door Seal - Upper on Door Driver Side or Passenger Side
1973-1979 Ford F-250 Driver & Passenger Side Glass Run Division Bar Channel

OEM-replacement glass run division bar channel for the Ford. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces Ford: D3TZ1021546A

$17.74
• SALE $12.95
Select Color/Material Options  
1973-1979 Ford F-250 Driver & Passenger Side Glass Run Division Bar Channel
1973-1979 Ford F-250 Driver & Passenger Side Upper Glass Run Channel

OEM-replacement upper glass run channel for the Ford. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces Ford: D8TZ1021536A

$14.96
• SALE $10.95
Select Color/Material Options  
1973-1979 Ford F-250 Driver & Passenger Side Upper Glass Run Channel
1967-1972 Ford F-250 Driver & Passenger Side Glass Run Division Bar Channel

OEM-replacement glass run division bar channel for the Ford. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces Ford: C7TZ8121546A

1953-1955 Ford F-250 Gas Gauge Wire Through Frame. For Sending Unit. 1" O.D.

Designed for 1953-1955 Ford F-100, F-250, and F-350 trucks, this gas gauge wire grommet measures 1" O.D. and is crafted to guide the sending unit wire securely through the frame. Made by Metro Moulded Parts, it features advanced rubber compounds that resist chemicals, sunlight, and ozone, ensuring long-lasting durability in harsh conditions. Its sleek black finish and precise design make it a perfect fit for your classic truck, maintaining both functionality and appearance. Backed by Metro’s 30-year Platinum Warranty, this part guarantees peace of mind for decades.

Features and Benefits
  • Protects the gas gauge wire from wear and damage.
  • Resists harsh environmental factors like sunlight and ozone.
  • Ensures a snug and secure fit for reliable performance.

(131 Total Products)