Ford F-250 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Ford F-250 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Ford F-250—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Ford F-250 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Ford F-250, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Ford F-250.

1953-1956 Ford F-250 Floor Plug Grommet. Used on Each Side of Seat.

Designed for 1953-1956 Ford F-100, F-250, and F-350 trucks, this floor plug grommet fits a 3/4" hole size and is used on each side of the seat to seal and protect openings. Made with state-of-the-art rubber compounds, it is resistant to chemicals, sunlight, and ozone, ensuring long-lasting durability and performance. Its sleek black finish provides a clean, professional look while effectively preventing dirt, moisture, and debris from entering the cabin. Installation is straightforward, as the grommet securely fits into the designated hole, creating a snug and reliable seal. Backed by Metro Moulded Parts' 30-year Platinum Warranty, this part offers peace of mind and confidence in its quality and longevity.

Features and Benefits
  • Fits snugly into 3/4" holes for a secure seal.
  • Protects against dirt, moisture, and debris.
  • Resistant to chemicals, sunlight, and ozone for durability.

1953-1956 Ford F-250 Mirror Hole Plug.

For panel trucks and trucks, this mirror hole plug is designed to fit a 1/2" wide by 1-5/8" long hole, making it a perfect solution for vehicles without side mirrors. Crafted with state-of-the-art rubber compounds, it is resistant to chemicals, sunlight, and ozone, ensuring long-lasting durability and performance. This plug is an excellent fit for 1953-1956 Ford F-100, F-250, and F-350 trucks, providing a clean and seamless look by covering unused mirror holes. Its sleek black finish blends effortlessly with the vehicle's exterior, enhancing its overall appearance. Backed by Metro's Platinum Warranty, this part is protected for 30 years, giving you peace of mind with your purchase.

Features and Benefits
  • Fits securely into 1/2" x 1-5/8" holes for a snug, reliable fit.
  • Made from durable rubber compounds for long-term resistance to wear.
  • Protects against chemical, sunlight, and ozone damage.
  • Enhances the vehicle's appearance by covering unused mirror holes.

1953-1956 Ford F-250 Special Purpose Grommet. Main Wiring Loom. 1-9/16" O.D.

Designed for 1948-1956 Ford F-Series Trucks, this special-purpose grommet is crafted to fit the main wiring loom with precision. Measuring 1-9/16" in outer diameter and featuring a 1/2" hole, it ensures a snug and secure fit for your wiring needs. Made from state-of-the-art rubber compounds, this grommet is built to resist chemicals, sunlight, and ozone, making it highly durable and long-lasting. Its sleek black finish blends seamlessly with your vehicle's components, offering both functionality and a clean appearance. Backed by Metro's 30-year warranty, you can trust in its quality and performance for decades to come.

Features and Benefits
  • Protects wiring from wear and tear.
  • Resists harsh environmental factors like sunlight and ozone.
  • Ensures a secure and precise fit for the main wiring loom.

1953-1956 Ford F-250 Glove Box Bumper. Two Used Per Truck. Each.

For 1953-1956 Ford F-100, F-250, and F-350 trucks, as well as Lincoln Capri, Cosmopolitan, Mark II, Premier, and Mercury Custom, Monterey, Montclair, and Medalist cars, this glove box bumper is a small but essential component designed to ensure a snug and secure fit for your glove box door. Measuring compactly to fit perfectly, this durable and long-lasting bumper is crafted from high-quality materials to withstand wear and tear over time. Two bumpers are used per truck, making installation straightforward and hassle-free. Positioned to cushion and protect the glove box door, it prevents rattling and ensures smooth operation. Backed by Metro’s Platinum 30-year warranty, this part guarantees peace of mind and reliability for decades.

Features and Benefits
  • Provides a secure and quiet glove box closure.
  • Made from durable materials for long-lasting performance.
  • Easy to install with a precise fit for 1953-1956 models.

$12.99
• SALE $10.95
Select Color/Material Options  
1953-1956 Ford F-250 Glove Box Bumper. Two Used Per Truck. Each.
1953-1956 Ford F-250 Wiper Motor Control Wire Grommet. Each.

Designed for 1949-1956 Ford F-Series Trucks, this wiper motor control wire grommet is a durable and reliable solution for protecting your vehicle’s wiring. Crafted by Metro Moulded Parts, it ensures a snug fit and long-lasting performance. This small yet essential component is made from high-quality materials, providing a secure seal to keep moisture, dirt, and debris out of your wiper motor wiring. Its compact, conical design allows for easy installation, making it a hassle-free replacement part. Specifically engineered for Ford F-1, F-2, F-3, F-4, F-100, F-250, and F-350 trucks from 1949 to 1956, this grommet is a perfect fit for restoring or maintaining your classic truck. Backed by Metro’s 30-year Platinum Warranty, you can trust in its quality and durability for decades to come.

Features and Benefits
  • Protects wiper motor wiring from moisture and debris.
  • Durable material ensures long-lasting performance.
  • Easy to install for a secure and snug fit.

$12.99
• SALE $10.95
Select Color/Material Options  
1953-1956 Ford F-250 Wiper Motor Control Wire Grommet. Each.

(131 Total Products)