Ford F-350 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Ford F-350 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Ford F-350—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Ford F-350 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Ford F-350, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Ford F-350.

1963-1964 Ford F-350 Flexible Glass-Run Channel. Flocked.

This flexible glass-run channel, designed for 1963-1964 Chevrolet C10, C20, C30, K10, and K20 Pickup Trucks as well as 1963-1964 Ford F-100, F-250, and F-350 Trucks, measures 60 inches in length and is flocked for a smooth, snug fit. Perfect for vehicles without framed side glass, it ensures a secure seal to keep out wind, water, and debris while reducing noise. The channel can be sectioned into two equal lengths for easier shipping, especially for overseas orders. Its accurate seal profiles and durable construction make it a reliable choice for restoring or maintaining your truck’s windows. Backed by a 90-day warranty, this part guarantees peace of mind with your purchase.

Features and Benefits
  • Provides a tight seal to block wind and water.
  • Flocked surface ensures smooth window operation.
  • Can be cut for easier installation or shipping.
  • Designed for a precise fit on classic trucks.

$295.49
• SALE $235.95
Select Color/Material Options  
1963-1964 Ford F-350 Flexible Glass-Run Channel. Flocked.
1980-1987 Ford F-350 Window Sweeper Kit. Fits 80-87 Ford Bronco and Truck 2 Door Extended/Standard.

This four piece set includes the inner and outer window felt beltline weatherstrips for each door side window. These strips wipe the side windows when the glass is lowered.

Features and Benefits
  • Accurate seal profiles
  • Superior form and function

$381.49
• SALE $304.95
Select Color/Material Options  
1980-1987 Ford F-350 Window Sweeper Kit. Fits 80-87 Ford Bronco and Truck 2 Door Extended/Standard.

(127 Total Products)