Ford F-350 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Ford F-350 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Ford F-350—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Ford F-350 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Ford F-350, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Ford F-350.

1961-1966 Ford F-350 Vent Window SL.

This vent window seal is designed specifically for 1961-1966 Ford F150 and F250 trucks. Crafted with precision using the latest advancements in CAD and CNC milling, it ensures a perfect 3D contour and an OEM-quality appearance. This seal fits snugly around the vent window, preventing water, dust, and air leaks, keeping your truck's interior protected from the elements. Its durable material is built to withstand years of use, maintaining its shape and effectiveness over time. Installation is straightforward, as it is designed to fit seamlessly into the original vent window frame, restoring the functionality and look of your classic Ford truck. Backed by Metro Moulded Parts' 90-day No Hassle Guarantee, you can trust in its quality and performance.

Features and Benefits
  • Designed for 1961-1966 Ford F150 and F250 trucks.
  • Prevents water, dust, and air leaks for a sealed interior.
  • Made with advanced CAD and CNC milling for a precise fit.

$198.0
• SALE $158.95
Select Color/Material Options  
1961-1966 Ford F-350 Vent Window SL.
1957 Ford F-350 Vent Window Weatherstrip Seals. For 1/2 Ton Pickups. 25" Long Each.

For 1957 Ford F-100, F-250, and F-350 trucks, these vent window seals are designed specifically for 1/2-ton pickups and measure 25 inches long each. Sold as a pair for both the right and left sides, these seals are crafted with precision using the latest advancements in CAD and CNC milling to ensure a perfect 3D contour and an OEM-quality fit. They are built to keep your truck’s vent windows sealed tightly, preventing water, dust, and wind from entering the cabin while maintaining the classic look of your vehicle. Installation is straightforward, as these seals are designed to fit seamlessly into the original window frame. Backed by Metro’s 30-year Platinum Warranty, you can trust in their durability and long-lasting performance.

Features and Benefits
  • Keeps water, dust, and wind out of your truck’s cabin.
  • Precision-engineered for a perfect fit and OEM-quality appearance.
  • Easy installation into the original window frame.

$201.49
• SALE $160.95
Select Color/Material Options  
1957 Ford F-350 Vent Window Weatherstrip Seals. For 1/2 Ton Pickups. 25" Long Each.
1956 Ford F-350 Vulcanized Windshield Weatherstrip Seal. Each.

For 1956 Ford F-100, F-250, and F-350 trucks, this vulcanized windshield seal is designed to provide a flawless fit and ensure a leak-free seal for your classic vehicle. Crafted with high-quality compounds, it is built to last for the lifetime of your truck, maintaining its durability and flexibility over time. This seal is engineered to fit snugly around the windshield, preventing water, dust, and air from entering the cabin, keeping your interior protected in all weather conditions. Its sleek black finish complements the vintage look of your truck while offering modern performance. Backed by Metro’s Platinum Warranty, this part is guaranteed for 30 years, giving you peace of mind and confidence in your purchase.

Features and Benefits
  • Ensures a perfect, leak-free seal for your windshield.
  • Made with premium materials for long-lasting durability.
  • Protects your truck’s interior from water, dust, and air intrusion.

$214.49
• SALE $171.95
Select Color/Material Options  
1956 Ford F-350 Vulcanized Windshield Weatherstrip Seal. Each.
1957-1967 Ford F-350 Rigid Division-Bar Channel.

This rigid division-bar channel, measuring 96 inches long, is designed for a wide range of 1957-1967 Ford vehicles, including cars, trucks, and vans like the Thunderbird, Fairlane, Ranchero, and F-100. Crafted with a durable heavy steel core, a stainless steel bead, and a soft pile lining, this part ensures a snug and secure fit while reducing noise and vibration. Its accurate seal profiles enhance weatherproofing, making it ideal for maintaining a tight seal against the elements. The channel can be sectioned into two or three equal lengths for easier overseas shipping, with a $20 special shipping charge applying to domestic orders. This part is backed by a 90-day No Hassle Guarantee, ensuring peace of mind with your purchase.

Features and Benefits
  • Provides a secure and durable seal for windows.
  • Reduces noise and vibration for a smoother ride.
  • Weatherproof design protects against the elements.
  • Flexible shipping options for international buyers.

$226.49
• SALE $180.95
Select Color/Material Options  
1957-1967 Ford F-350 Rigid Division-Bar Channel.
1953-1956 Ford F-350 Vulcanized Rear Windshield Weatherstrip Seal.

For 1953-1956 Ford F-100, F-250, and F-350 trucks, this vulcanized rear windshield seal is designed specifically for models without a wrap-around rear window. Crafted with high-quality compounds, it ensures a perfect, leak-free seal that will last the lifetime of your vehicle. This durable seal fits snugly around the rear windshield, providing excellent protection against water and weather, keeping your truck’s interior dry and secure. Its precise fitment guarantees easy installation, making it a reliable choice for restoring or maintaining your classic Ford truck. Backed by Metro Moulded Parts' Platinum Warranty, this seal is covered for 30 years, giving you peace of mind with your purchase.

Features and Benefits
  • Creates a watertight seal to prevent leaks.
  • Made from long-lasting, high-quality materials.
  • Designed for easy installation on compatible trucks.

$242.49
• SALE $193.95
Select Color/Material Options  
1953-1956 Ford F-350 Vulcanized Rear Windshield Weatherstrip Seal.

(127 Total Products)