GMC Sierra 2500 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals
Stop leaks, drafts, and road noise in your GMC Sierra 2500 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your GMC Sierra 2500—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.
Our GMC Sierra 2500 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.
Use the Vehicle Selector above to find the correct weatherstrip for your GMC Sierra 2500, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your GMC Sierra 2500.
OEM-replacement door seal for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.
Replaces GM: 15758703, 15766539, 15956393, 15956394, 15973659
OEM-replacement door seal for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.
Replaces GM: 15063155, 15244250
- Fitment: Driver and Passenger Side
- OEM-replacement door seal for the 2007-2007 GMC Sierra 2500 (GMT900)
- EPDM rubber -- resists UV, heat, ozone, and moisture
- Restores factory seal to eliminate wind noise, water leaks, and dust
- Direct fit -- installs in the factory channel without modification
OEM-replacement belt weatherstrip kit for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.
Replaces GM: 15704112, 15735502
This seal is designed for 4-door crew cab trucks and presses onto the upper part of the body, ensuring a snug and secure fit. Made from high-quality ozone-resistant EPDM rubber, it is built to match the original specifications for durability and long-lasting performance. The accurate seal profile ensures a tight fit, effectively keeping out water, dust, and noise, while maintaining the vehicle's original appearance. This hard-to-find part is crafted from durable EPDM polymer, making it resistant to wear and tear over time. It fits a wide range of models, including 2000-2006 Chevrolet Silverado, Suburban, and GMC Sierra trucks, as well as 2002-2006 Cadillac Escalade EXT trucks. Backed by a 90-day warranty, this seal is a reliable replacement for maintaining your truck's comfort and protection.
Features and Benefits- Provides a tight seal to block water, dust, and noise.
- Made from ozone-resistant EPDM rubber for durability.
- Matches original specifications for a perfect fit.
- Fits a wide range of 2000-2006 GM truck models.
(27 Total Products)