GMC Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your GMC with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your GMC —restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our GMC weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your GMC , or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your GMC .

2000-2006 GMC Yukon XL 2500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV, Fits Passenger Side Only, Each.

For 4-door crew cab trucks, this seal, replacing OEM #21993936, is designed to press onto the upper part of the body, ensuring a snug and reliable fit. Crafted from high-quality ozone-resistant EPDM rubber, it offers durability and long-lasting performance, even in harsh weather conditions. The accurate seal profile ensures a perfect fit, making it an essential replacement for maintaining your vehicle's integrity. This hard-to-find part is compatible with 2000-2006 Chevrolet Silverado 1500, Suburban 2500, Tahoe, GMC Yukon, Yukon XL 2500, and Cadillac Escalade trucks. Its durable EPDM polymer construction resists wear and tear, providing excellent sealing to keep out water, dust, and noise. Backed by a 90-day warranty, this seal is a reliable choice for restoring your truck's functionality and comfort.

Features and Benefits
  • Made from ozone-resistant EPDM rubber for durability.
  • Ensures a tight seal to protect against water, dust, and noise.
  • Designed for a precise fit on 4-door crew cab trucks.
  • Hard-to-find replacement part for 2000-2006 models.

$89.99
• SALE $71.95
Select Color/Material Options  
2000-2006 GMC Yukon XL 2500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV, Fits Passenger Side Only, Each.
2004-2006 GMC Sierra 1500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV, Fits Driver Side Only, Each.

This seal is designed for 4-door crew cab trucks and presses onto the upper part of the body, ensuring a snug and secure fit. Made from high-quality ozone-resistant EPDM rubber, it is built to match the original specifications for durability and long-lasting performance. The accurate seal profile ensures a tight fit, effectively keeping out water, dust, and noise, while maintaining the vehicle's original appearance. This hard-to-find part is crafted from durable EPDM polymer, making it resistant to wear and tear over time. It fits a wide range of models, including 2000-2006 Chevrolet Silverado, Suburban, and GMC Sierra trucks, as well as 2002-2006 Cadillac Escalade EXT trucks. Backed by a 90-day warranty, this seal is a reliable replacement for maintaining your truck's comfort and protection.

Features and Benefits
  • Provides a tight seal to block water, dust, and noise.
  • Made from ozone-resistant EPDM rubber for durability.
  • Matches original specifications for a perfect fit.
  • Fits a wide range of 2000-2006 GM truck models.

$89.99
• SALE $71.95
Select Color/Material Options  
2004-2006 GMC Sierra 1500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV, Fits Driver Side Only, Each.
2001-2006 GMC Sierra 1500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV, Fits Driver Side Only, Each.

This seal is designed for 4-door crew cab trucks and presses onto the upper part of the body, ensuring a snug and secure fit. Made from high-quality ozone-resistant EPDM rubber, it is built to match the original specifications for durability and long-lasting performance. The accurate seal profile ensures a tight fit, effectively keeping out water, dust, and noise, while maintaining the vehicle's original appearance. This hard-to-find part is crafted from durable EPDM polymer, making it resistant to wear and tear over time. It fits a wide range of models, including 2000-2006 Chevrolet Silverado, Suburban, and GMC Sierra trucks, as well as 2002-2006 Cadillac Escalade EXT trucks. Backed by a 90-day warranty, this seal is a reliable replacement for maintaining your truck's comfort and protection.

Features and Benefits
  • Provides a tight seal to block water, dust, and noise.
  • Made from ozone-resistant EPDM rubber for durability.
  • Matches original specifications for a perfect fit.
  • Fits a wide range of 2000-2006 GM truck models.

$89.99
• SALE $71.95
Select Color/Material Options  
2001-2006 GMC Sierra 1500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV, Fits Driver Side Only, Each.
2001-2006 GMC Sierra 2500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV, Fits Driver Side Only, Each.

This seal is designed for 4-door crew cab trucks and presses onto the upper part of the body, ensuring a snug and secure fit. Made from high-quality ozone-resistant EPDM rubber, it is built to match the original specifications for durability and long-lasting performance. The accurate seal profile ensures a tight fit, effectively keeping out water, dust, and noise, while maintaining the vehicle's original appearance. This hard-to-find part is crafted from durable EPDM polymer, making it resistant to wear and tear over time. It fits a wide range of models, including 2000-2006 Chevrolet Silverado, Suburban, and GMC Sierra trucks, as well as 2002-2006 Cadillac Escalade EXT trucks. Backed by a 90-day warranty, this seal is a reliable replacement for maintaining your truck's comfort and protection.

Features and Benefits
  • Provides a tight seal to block water, dust, and noise.
  • Made from ozone-resistant EPDM rubber for durability.
  • Matches original specifications for a perfect fit.
  • Fits a wide range of 2000-2006 GM truck models.

$89.99
• SALE $71.95
Select Color/Material Options  
2001-2006 GMC Sierra 2500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV, Fits Driver Side Only, Each.
1996 GMC G3500 Door Weatherstrip Seal, 96-02 Chevrolet Express / GMC Savana Vans, Fits Front Left or Right.

Designed for full-size vans, this door seal fits the front left or right side of 1996-2002 Chevrolet Express and GMC Savana 1500, 2500, and 3500 models. Crafted from durable EPDM polymer, it ensures a snug fit on the door, effectively reducing drafts and road noise for a quieter and more comfortable ride. The accurate seal profile enhances its performance, keeping out moisture and debris while maintaining a clean and secure closure. Installation is straightforward, as it is designed to fit perfectly on the door edge, providing a reliable barrier against the elements. Backed by a 30-year warranty from SuperSoft, this seal offers long-lasting protection and peace of mind.

Features and Benefits
  • Reduces drafts and road noise for a quieter cabin.
  • Made from durable EPDM polymer for long-term use.
  • Fits front left or right side doors for easy installation.

$91.99
• SALE $73.95
Select Color/Material Options  
1996 GMC G3500 Door Weatherstrip Seal, 96-02 Chevrolet Express / GMC Savana Vans, Fits Front Left or Right.

(1091 Total Products)