GMC Sierra 3500 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your GMC Sierra 3500 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your GMC Sierra 3500—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our GMC Sierra 3500 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your GMC Sierra 3500, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your GMC Sierra 3500.

2007-2014 GMC Sierra 3500 Auxiliary Weatherstrip Upper Kit

OEM-replacement auxiliary weatherstrip upper kit for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 20816087, 20816088

$272.99
• SALE $189.95
Select Color/Material Options  
2007-2014 GMC Sierra 3500 Auxiliary Weatherstrip Upper Kit
2007-2013 GMC Sierra 3500 Drip Rail Weatherstrip Kit

OEM-replacement drip rail weatherstrip kit for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 20816085, 20816086

$240.75
• SALE $166.95
Select Color/Material Options  
2007-2013 GMC Sierra 3500 Drip Rail Weatherstrip Kit
2010-2014 GMC Sierra 3500 Drip Rail Weatherstrip Kit

OEM-replacement drip rail weatherstrip kit for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 20816083, 20816084

$234.26
• SALE $162.95
Select Color/Material Options  
2010-2014 GMC Sierra 3500 Drip Rail Weatherstrip Kit
2007-2014 GMC Sierra 3500 Auxiliary Weatherstrip Upper, Front

OEM-replacement auxiliary weatherstrip upper, front for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 20816088

$131.67
• SALE $91.95
Select Color/Material Options  
2007-2014 GMC Sierra 3500 Auxiliary Weatherstrip Upper, Front
2001-2005 GMC Sierra 3500 Driver & Passenger Side Belt Weatherstrip Kit

OEM-replacement belt weatherstrip kit for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15104012, 15104013, 15136069, 15136070

$118.14
• SALE $81.95
Select Color/Material Options  
2001-2005 GMC Sierra 3500 Driver & Passenger Side Belt Weatherstrip Kit

(20 Total Products)