GMC Sierra 3500 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your GMC Sierra 3500 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your GMC Sierra 3500—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our GMC Sierra 3500 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your GMC Sierra 3500, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your GMC Sierra 3500.

2001-2002 GMC Sierra 3500 Driver & Passenger Side Belt Weatherstrip Kit - Inner & Outer Driver Side & Passenger Side

OEM-replacement belt weatherstrip kit - inner & outer driver side & passenger side for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15704112, 15735502, 15991405, 15991406

$90.46
• SALE $62.95
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2001-2002 GMC Sierra 3500 Driver & Passenger Side Belt Weatherstrip Kit - Inner & Outer Driver Side & Passenger Side
2001-2002 GMC Sierra 3500 Driver & Passenger Side Belt Weatherstrip Kit - Outer Driver side and Passenger side

OEM-replacement belt weatherstrip kit - outer driver side and passenger side for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15991405, 15991406

$72.72
• SALE $50.95
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2001-2002 GMC Sierra 3500 Driver & Passenger Side Belt Weatherstrip Kit - Outer Driver side and Passenger side
2007-2010 GMC Sierra 3500 Driver & Passenger Side Rear Door Opening Weatherstrip

OEM-replacement rear door opening weatherstrip for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22766417

$59.12
• SALE $40.95
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2007-2010 GMC Sierra 3500 Driver & Passenger Side Rear Door Opening Weatherstrip
2001-2002 GMC Sierra 3500 (GMT800) Rear Outer Belt Weatherstrip

  • Fitment: Driver and Passenger Side -- Rear -- Sold as: 2-Piece Kit
  • OEM-replacement weatherstrip kit for the 2001-2002 GMC Sierra 3500 (GMT800)

$58.53
• SALE $40.95
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2001-2002 GMC Sierra 3500 (GMT800) Rear Outer Belt Weatherstrip
2001-2002 GMC Sierra 3500 Driver & Passenger Side Door Seal

OEM-replacement door seal for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 15758703, 15766539, 15956393, 15956394, 15973659

$53.21
• SALE $36.95
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2001-2002 GMC Sierra 3500 Driver & Passenger Side Door Seal

(20 Total Products)