GMC Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your GMC with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your GMC —restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our GMC weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your GMC , or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your GMC .

2007 GMC Sierra 3500 Classic Upper Door Weatherstrip Seal, 00-07 GM Full Size Truck, Extended Cab, On Body.

For extended cab GM full-size trucks from 2000 to 2007, this upper door seal pair (OEM #15054569 & #15044908) is designed to mount on the body and seal against the doors, ensuring a snug fit. Made from high-quality, ozone-resistant EPDM rubber, these seals are built to last and maintain their flexibility over time. They feature an accurate seal profile and incorporate all original details for a precise fit, reducing drafts and road noise for a quieter and more comfortable ride. This pair includes seals for both the left and right sides, making installation straightforward and ensuring complete coverage. Compatible with Chevrolet Silverado and GMC Sierra models from 2000 to 2007, including Classic editions, this part is a reliable replacement for worn or damaged seals. Backed by a 90-day warranty, this product ensures peace of mind with its durability and performance.

Features and Benefits
  • Reduces drafts and road noise for a quieter cabin.
  • Made from durable, ozone-resistant EPDM rubber for long-lasting use.
  • Designed for a precise fit with accurate seal profiles.
  • Easy installation with seals for both left and right sides included.

$148.49
• SALE $118.95
Select Color/Material Options  
2007 GMC Sierra 3500 Classic Upper Door Weatherstrip Seal, 00-07 GM Full Size Truck, Extended Cab, On Body.
2000-2006 GMC Yukon Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV 4 Door, On Body, Pair.

Designed for the 2000-2006 Cadillac Escalade, Chevrolet Suburban 1500/2500, Chevrolet Tahoe, GMC Yukon, and GMC Yukon XL 1500/2500 trucks, these high-quality door seals are crafted to mount on the upper part of the body, ensuring a snug fit against the doors. Made from durable, ozone-resistant EPDM rubber, these seals are built to last and maintain their flexibility over time. Their precise design incorporates all original details, providing an accurate seal profile that reduces drafts and road noise, enhancing your driving comfort. This pair includes seals for both the left and right sides, offering a complete solution for your vehicle. Backed by a 90-day warranty, these seals are a reliable choice for restoring or maintaining your truck’s weatherproofing and sound insulation.

Features and Benefits
  • Made from ozone-resistant EPDM rubber for long-lasting durability.
  • Reduces drafts and road noise for a quieter ride.
  • Precisely designed for a perfect fit and seal.
  • Includes seals for both left and right sides for complete coverage.

$153.99
• SALE $122.95
Select Color/Material Options  
2000-2006 GMC Yukon Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV 4 Door, On Body, Pair.
2000-2006 GMC Yukon XL 1500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV 4 Door, On Body, Pair.

Designed for the 2000-2006 Cadillac Escalade, Chevrolet Suburban 1500/2500, Chevrolet Tahoe, GMC Yukon, and GMC Yukon XL 1500/2500 trucks, these high-quality door seals are crafted to mount on the upper part of the body, ensuring a snug fit against the doors. Made from durable, ozone-resistant EPDM rubber, these seals are built to last and maintain their flexibility over time. Their precise design incorporates all original details, providing an accurate seal profile that reduces drafts and road noise, enhancing your driving comfort. This pair includes seals for both the left and right sides, offering a complete solution for your vehicle. Backed by a 90-day warranty, these seals are a reliable choice for restoring or maintaining your truck’s weatherproofing and sound insulation.

Features and Benefits
  • Made from ozone-resistant EPDM rubber for long-lasting durability.
  • Reduces drafts and road noise for a quieter ride.
  • Precisely designed for a perfect fit and seal.
  • Includes seals for both left and right sides for complete coverage.

$153.99
• SALE $122.95
Select Color/Material Options  
2000-2006 GMC Yukon XL 1500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV 4 Door, On Body, Pair.
2000-2006 GMC Yukon XL 2500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV 4 Door, On Body, Pair.

Designed for the 2000-2006 Cadillac Escalade, Chevrolet Suburban 1500/2500, Chevrolet Tahoe, GMC Yukon, and GMC Yukon XL 1500/2500 trucks, these high-quality door seals are crafted to mount on the upper part of the body, ensuring a snug fit against the doors. Made from durable, ozone-resistant EPDM rubber, these seals are built to last and maintain their flexibility over time. Their precise design incorporates all original details, providing an accurate seal profile that reduces drafts and road noise, enhancing your driving comfort. This pair includes seals for both the left and right sides, offering a complete solution for your vehicle. Backed by a 90-day warranty, these seals are a reliable choice for restoring or maintaining your truck’s weatherproofing and sound insulation.

Features and Benefits
  • Made from ozone-resistant EPDM rubber for long-lasting durability.
  • Reduces drafts and road noise for a quieter ride.
  • Precisely designed for a perfect fit and seal.
  • Includes seals for both left and right sides for complete coverage.

$153.99
• SALE $122.95
Select Color/Material Options  
2000-2006 GMC Yukon XL 2500 Upper Door Weatherstrip Seal, 00-06 GM Full Size SUV 4 Door, On Body, Pair.
2007-2014 GMC Yukon TG 10-T - Liftgate Weatherstrip Seal, Push-On Trim Style, On Body, Each.

Designed for 4-door trucks, this liftgate seal fits 2007-2014 Cadillac Escalade (ESV, EXT), Chevrolet Tahoe/Suburban (1500, 2500), and GMC Yukon (XL 1500, XL 2500) models, replacing OEM #22775503. Crafted from durable EPDM polymer, this seal ensures a snug fit to keep your climate-controlled air inside while blocking out weather, drafts, and road noise. Its robust construction resists wear and tear, providing long-lasting performance. The seal is easy to install, fitting securely around the liftgate to maintain a tight barrier against the elements. With its sleek black finish, it blends seamlessly with your vehicle's design, enhancing both function and appearance. Backed by a 90-day warranty, this part offers peace of mind and reliable protection for your vehicle.

Features and Benefits
  • Keeps out weather and drafts for a comfortable interior.
  • Reduces road noise for a quieter ride.
  • Made from durable EPDM polymer for long-lasting use.
  • Easy to install and fits securely for reliable performance.

$157.99
• SALE $126.95
Select Color/Material Options  
2007-2014 GMC Yukon TG 10-T - Liftgate Weatherstrip Seal, Push-On Trim Style, On Body, Each.

(1091 Total Products)