GMC Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your GMC with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your GMC —restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our GMC weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your GMC , or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your GMC .

1976-1991 GMC K5 Jimmy (Squarebody / K5) Inner Outer Weatherstrip Seal

  • Fitment: Sold as: 2-Piece Kit
  • OEM-replacement door window seal for the 1976-1991 GMC K5 Jimmy (Squarebody)
  • EPDM rubber construction -- resists UV, heat, ozone, and moisture
  • Direct OEM replacement -- no trimming or modification required

1967-1972 GMC K5 Jimmy (Squarebody) Upper Vent Window Division Bar Channel Seal Part KG1006

  • Fitment: Driver and Passenger Side -- Sold as: 2-Piece Kit
  • Fitment note: Belts with Vents
  • OEM-replacement glass run kit for the 1967-1972 GMC K5 Jimmy
  • EPDM rubber construction -- resists UV, heat, ozone, and moisture
  • Direct OEM replacement -- no trimming or modification required

2007-2014 GMC Yukon Driver & Passenger Side Door Seal on body

OEM-replacement door seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22766409

2007-2014 GMC Yukon XL 1500 Driver & Passenger Side Door Seal on body

OEM-replacement door seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22766409

2007-2013 GMC Yukon XL 2500 Driver & Passenger Side Door Seal on body

OEM-replacement door seal on body for Cadillac / Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22766409

(1091 Total Products)