GMC Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your GMC with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your GMC —restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our GMC weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your GMC , or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your GMC .

1966-1966 GMC K1000 Driver & Passenger Side Glass Run Kit - Division Bar Driver side and Passenger side

OEM-replacement glass run kit - division bar driver side and passenger side for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

$57.46
• SALE $39.95
Select Color/Material Options  
1966-1966 GMC K1000 Driver & Passenger Side Glass Run Kit - Division Bar Driver side and Passenger side
1979-1986 GMC K3500 Driver & Passenger Side Glass Run Kit

OEM-replacement glass run kit for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 14027777, 14027778

$57.44
• SALE $39.95
Select Color/Material Options  
1979-1986 GMC K3500 Driver & Passenger Side Glass Run Kit
1973-1991 GMC K5 Jimmy (Squarebody / K5) Glass Run Window Channel Seal

  • Fitment: Driver and Passenger Side -- Rear -- Sold as: 2-Piece Kit
  • Replacement glass run kit for the 1973-1991 GMC K5 Jimmy (Squarebody)
  • EPDM rubber -- keeps window glass tracking smoothly and sealing correctly
  • Eliminates window rattle, wind noise, and water leaks around the glass
  • Direct OEM replacement -- no trimming required

$57.44
• SALE $39.95
Select Color/Material Options  
1973-1991 GMC K5 Jimmy (Squarebody / K5) Glass Run Window Channel Seal
2007-2013 GMC Sierra 1500 Driver & Passenger Side Front Door Opening Weatherstrip

OEM-replacement front door opening weatherstrip for Chevrolet / GMC. Precision-molded from EPDM rubber to resist UV, heat, ozone, and moisture — restoring the factory seal and eliminating wind noise, water leaks, and drafts.

Replaces GM: 22766400

$56.99
• SALE $39.95
Select Color/Material Options  
2007-2013 GMC Sierra 1500 Driver & Passenger Side Front Door Opening Weatherstrip
1992-1994 GMC Yukon Passenger Side Passenger Side Glass Run Channel Seal

  • Fitment: Passenger Side
  • Replacement window channel for the 1992-1994 GMC Yukon
  • EPDM rubber -- keeps window glass tracking smoothly and sealing correctly
  • Eliminates window rattle, wind noise, and water leaks around the glass
  • Direct OEM replacement -- no trimming required

$56.66
• SALE $39.95
Select Color/Material Options  
1992-1994 GMC Yukon Passenger Side Passenger Side Glass Run Channel Seal

(1091 Total Products)