Ford F-350 Weatherstrip & Seals - OEM-Fit Door, Trunk & Window Seals

Stop leaks, drafts, and road noise in your Ford F-350 with precision-fit replacement weatherstrip and seals designed specifically for your vehicle. Each seal is engineered to match the original profile and mounting groove of your Ford F-350—restoring a tight, quiet seal around your doors, trunk, hatch, and windows.

Our Ford F-350 weatherstrip is manufactured from durable, weather-resistant rubber compounds such as EPDM, engineered for an exact OEM-quality fit and finish. These materials resist sunlight, ozone, and chemical exposure while maintaining flexibility across temperature extremes, so your new seals stay soft and pliable instead of cracking or hardening the way factory-original rubber does over time.

Use the Vehicle Selector above to find the correct weatherstrip for your Ford F-350, or browse below to explore available options. Whether you’re chasing down a stubborn water leak or completing a full restoration, Factory Interiors makes it easy to achieve a tight, factory-quality seal with precision-fit weatherstrip for your Ford F-350.

1953-1956 Ford F-350 Cowl Vent Weatherstrip Seal. Perfect Reproduction.

For 1953-1956 Ford F-100, F-250, and F-350 trucks, this cowl vent seal is a perfect reproduction designed to fit seamlessly with a 13-1/2" diameter rubber ring. Crafted by Metro Moulded Parts, it is made with over 50 tons of pressure to ensure precise detailing and a flawless fit. This durable seal is designed to prevent water, dirt, and debris from entering the cowl vent area, keeping your truck's interior protected and maintaining its classic look. Installation is straightforward, with clear instructions included, making it easy to replace your old or worn-out seal. Backed by Metro's Platinum Warranty, this part is covered for 30 years, giving you peace of mind and confidence in its long-lasting quality.

Features and Benefits
  • Keeps water and debris out of the cowl vent area.
  • Made with high-pressure molding for exact detailing.
  • Includes installation instructions for easy setup.

$74.99
• SALE $59.95
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1953-1956 Ford F-350 Cowl Vent Weatherstrip Seal. Perfect Reproduction.
1953-1956 Ford F-350 Clutch and Brake Pedal Pads.

For classic Ford cars and trucks, these clutch and brake pedal pads are a perfect fit, measuring 3 inches in diameter and designed for 1933-1942 Ford Model 40, 48, 68, 74, 78, 81A, Deluxe, Standard, and Mercury Series cars, as well as 1946-1956 Ford F-Series trucks. Made by Metro Moulded Parts, these pads feature a molded steel core with a threaded stud for secure installation, ensuring durability and reliability. Their detailed design and proper curves replicate the original look, enhancing the authenticity of your vehicle’s interior. These pads are easy to install, slipping on effortlessly to provide a firm grip and a polished finish. Backed by a 90-day warranty, they offer peace of mind and quality assurance.

Features and Benefits
  • Designed to fit securely with a molded steel core and threaded stud.
  • Matches the original look with detailed craftsmanship.
  • Easy installation with a slip-on design.
  • Durable and reliable for long-lasting performance.

$99.99
• SALE $79.95
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1953-1956 Ford F-350 Clutch and Brake Pedal Pads.
1961-1966 Ford F-350 Windshield Weatherstrip Seal, 61-66 Ford Full Size Pickup, Without Trim Groove, Each.

For 1961-1966 Ford full-size pickup trucks, this windshield seal is designed without a trim groove and ensures a precise fit with its accurate seal profile. Made from durable EPDM polymer, it effectively reduces drafts and road noise, enhancing your driving comfort. This seal is crafted to match all original details, ensuring a seamless installation and a factory-like appearance. It fits a wide range of models, including the Ford F-100, F-250, F-350, and up to the F-950 for the years 1961 through 1966. Built to last, this seal provides reliable protection against the elements, keeping your windshield secure and your cabin quieter. Backed by a 90-day no-hassle warranty, this part is a dependable choice for restoring your truck's functionality and comfort.

Features and Benefits
  • Provides a precise and secure windshield seal.
  • Reduces drafts and road noise for a quieter ride.
  • Made from durable EPDM polymer for long-lasting performance.
  • Matches original details for a factory-like fit and appearance.

$101.99
• SALE $81.95
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1961-1966 Ford F-350 Windshield Weatherstrip Seal, 61-66 Ford Full Size Pickup, Without Trim Groove, Each.
1973-1979 Ford F-350 Rear Window Weatherstrip Seal, '73-'79 Ford F Series Truck Without Trim Groove.

This weatherstrip does not work with original sliders. For the 1973-1979 Ford F-Series Trucks, this rear window seal is designed specifically for models without a trim groove and does not work with original sliders. Crafted from durable EPDM polymer, it ensures a snug, accurate fit to keep drafts, water, and road noise out of your cab. Proudly made in the USA, this seal is built to last and maintain its flexibility over time, providing reliable performance in all weather conditions. Its precise profile makes installation straightforward, fitting securely around the rear window to restore a clean, factory-like appearance. Compatible with Ford F-100, F-150, F-250, and F-350 trucks from 1973 to 1979, this seal is an essential upgrade for maintaining comfort and protecting your truck’s interior. Backed by a 90-day warranty, it’s a no-hassle solution for a better driving experience.

Features and Benefits
  • Reduces drafts and road noise for a quieter ride.
  • Made from long-lasting EPDM polymer for durability.
  • Fits securely to prevent water leaks and protect the interior.
  • Proudly made in the USA for quality you can trust.

$118.49
• SALE $94.95
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1973-1979 Ford F-350 Rear Window Weatherstrip Seal, '73-'79 Ford F Series Truck Without Trim Groove.
1961-1966 Ford F-350 Door Weatherstrip Seal, 61-66 Ford Full Size Pickup Trucks, On Body, Pair.

For 1961-1966 Ford full-size pickup trucks, this pair of on-body door seals is designed to provide a precise fit and exceptional performance. Crafted from durable EPDM polymer, these seals feature an accurate profile that ensures a snug fit, effectively reducing drafts and road noise for a quieter and more comfortable ride. Unlike solid sponge-type seals, these are hollowed out to allow your doors to close effortlessly without added resistance. These seals are specifically engineered for models including the Ford F-100, F-250, F-350, F-500, F-600, F-700, F-750, F-800, F-850, F-950, N-Series, NT-Series, and T-Series trucks from 1961 to 1966. Easy to install, they mount directly onto the body of your truck, restoring a tight seal that keeps out wind, water, and debris. Backed by a 90-day hassle-free warranty, this product ensures peace of mind with every purchase.

Features and Benefits
  • Reduces drafts and road noise for a quieter cabin.
  • Hollow design ensures doors close smoothly.
  • Made from durable EPDM polymer for long-lasting performance.
  • Easy installation directly onto the truck body.

$138.49
• SALE $110.95
Select Color/Material Options  
1961-1966 Ford F-350 Door Weatherstrip Seal, 61-66 Ford Full Size Pickup Trucks, On Body, Pair.

(127 Total Products)